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145 N. Antrim way
Greencastle, PA 17225
Call us at 717-597-2426
Visit us monday-friday 9-6
saturday 9-1
Carl's Brick Exterior

serving our local community

since 1825

Since 1825, Carl’s Drug Store has been a locally owned and operated pharmacy serving Greencastle, PA, and surrounding communities.


At Carl’s Drug Store, we are dedicated to offering you the personalized service you deserve. Whether it’s prescription medications or over-the-counter products, we are here to answer all your questions. Here, you’re never just a number or a face in the crowd - you’re family!


We publish free monthly newsletters via email and highlight newsletter topics here. 


We will start publishing free monthly newsletters via email soon. Don't miss out and sign up using the link bellow!

Are You Ready to make the switch?
Refills made easy

Once you download the Rx365 app, you will be able to:
• View your medications to see which ones have refills and which ones have expired or have no refills.
• Request prescription refills.
• Securely chat with pharmacy staff members.
• Enter your insurance information and upload your insurance cards.
• Transfer prescriptions from other pharmacies to Carl's Drug Store.
• Print your prescription tax report for the year.
To download the app to your smart phone, click the icons below or search for Rx365 in the App Store or on Google Play. You will need one of your prescription numbers to set up your profile. You can find this number on any of your prescription bottles.